Evidenzbasiert. Wirksam. Innovativ. elevida.

Digitale Hilfe für Patienten mit Fatigue bei MS.

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elevida auf einen Blick

Zur Reduktion von Symptomen einer Fatigue bei MS

Verschreibungsfähiges Medizinprodukt

In Studie erwiesene Wirksamkeit (NNT: 3,4)¹

Zuzahlungsfrei für Patienten

Niederschwellig und ohne Wartezeit

elevida verschreiben

Indikationen

G35 Multiple Sklerose [Encephalomyelitis disseminata]

elevida auf Rezeptvorlage Muster 16 eintragen

Pharmazentralnummer (PZN) 17161032

Verordnungsdauer 90 Tage (mindestens zweimalige Verordnung empfohlen)

EVIDENZ ALS ERFOLGSREZEPT

Das Fatigue-Syndrom bezeichnet eine außergewöhnlich starke Erschöpfbarkeit, unter der ein Großteil der MS-Betroffenen leidet und die bereits früh im Krankheitsverlauf auftreten kann. 75% der MS-Patienten¹, die an Fatigue leiden, beschreiben diese als ihre größte Lebenseinschränkung. Eine wirksame medikamentöse Behandlung fehlt bisher².

elevida ist das erste Online-Programm, das in einer klinischen Studie nachweisen konnte, die Symptome der Fatigue bei MS deutlich zu reduzieren (NNT: 3,4). Das führte zu einer dauerhaften Aufnahme in das Verzeichnis verschreibungsfähiger digitaler Gesundheitsanwendungen (DiGA).

WIE FUNKTIONIERT ELEVIDA?

elevida zeigt dem Patienten verschiedene Wege, mit Fatigue besser umzugehen und wieder mehr Lebensqualität zu verspüren. Im dynamischen Dialog zwischen Patient und Programm geschieht dies durch Information, Reflexion und Anleitung zu konkreten Übungen.

Quellen für die in elevida umgesetzten medizinischen Inhalte

Quellen anzeigen

¹Pöttgen J, et al. J Neurol Neurosurg Psychiatry 2018;0:1–7. doi:10.1136/jnnp-2017-317463

² Asano M, Finlayson ML. Meta-analysis of three different types of fatigue management interventions for people with multiple sclerosis: exercise, education, and medication. Mult Scler Int 2014;2014:1–12.

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Benedict RH, Munschauer F, Linn R, et al. Screening for multiple sclerosis cognitive impairment using a self-administered 15-item questionnaire. Mult Scler 2003;9:95–101.

Braley TJ, Chervin RD. Fatigue in multiple sclerosis: mechanisms, evaluation, and treatment. Sleep. 2010 Aug;33(8):1061-7.

Cakt BD, Nacir B, Genç H et al. Cycling progressive resistance training for people with multiple sclerosis: a randomized controlled study. Am J Phys Med Rehabil. 2010 Jun;89(6):446-57.

Cella M, Chalder T. Measuring fatigue in clinical and community settings. J Psychosom Res 2010;69:17–22.

Chwastiak LA, Gibbons LE, Ehde DM, et al. Fatigue and psychiatric illness in a large community sample of persons with multiple sclerosis. J Psychosom Res 2005;59:291–8.

Cosio D, Jin L, Siddique J, Mohr DC. The effect of telephone-administered cognitive-behavioral therapy on quality of life among patients with multiple sclerosis. Ann Behav Med. 2011 Apr;41(2):227-34.

Dalgas U, Stenager E, Jakobsen J et al. Fatigue, mood and quality of life improve in MS patients after progressive resistance training. Mult Scler. 2010 Apr;16(4):480-90.

Drummond LM. CBT for Adults: A Practical Guide for Clinicians. RCPsych Publications: London. 2014.

Dryden W, Branch R (Eds.). The CBT handbook. Sage: London. 2011.

Finlayson M, Preissner K, Cho C et al. Randomized trial of a teleconference-delivered fatigue management program for people with multiple sclerosis. Mult Scler. 2011 Sep;17(9):1130-40.

Fisk JD, Pontefract A, Ritvo PG, et al. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci 1994;21:9–14.

Ghahari S, Leigh Packer T, Passmore AE. Effectiveness of an online fatigue self-management programme for people with chronic neurological conditions: a randomized controlled trial. Clin Rehabil. 2010 Aug;24(8):727-44.

Gold SM, Schulz H, Stein H, et al. Responsiveness of patient-based and external rating scales in multiple sclerosis: head-to-head comparison in three clinical settings. J Neurol Sci 2010;290–102–6.

Gold SM, Heesen C, Schulz H, et al. Disease specific quality of life instruments in multiple sclerosis: validation of the Hamburg Quality of Life Questionnaire in Multiple Sclerosis (HAQUAMS). Mult Scler 2001;7:119–30.

Grossman P, Kappos L, Gensicke H et al. MS quality of life, depression, and fatigue improve after mindfulness training: a randomized trial. Neurology. 2010 Sep 28;75(13):1141-9.

Hayes HA, Gappmaier E, LaStayo PC. Effects of high-intensity resistance training on strength, mobility, balance, and fatigue in individuals with multiple sclerosis: a randomized controlled trial. J Neurol Phys Ther. 2011 Mar;35(1):2-10.

Hebert JR, Corboy JR, Manago MM et al. Effects of vestibular rehabilitation on multiple sclerosis-related fatigue and upright postural control: a randomized controlled trial. Phys Ther. 2011 Aug;91(8):1166-83.

Hofmann SG. An introduction to modern CBT: Psychological solutions to mental health problems. John Wiley & Sons: Chichester. 2011.

Hohol MJ, Orav EJ, Weiner HL. Disease steps in multiple sclerosis: a simple approach to evaluate disease progression. Neurology 1995;45:251–5.

Hugos CL, Copperman LF, Fuller BE et al. Clinical trial of a formal group fatigue program in multiple sclerosis. Mult Scler. 2010 Jun;16(6):724-32.

Kargarfard M, Etemadifar M, Baker P et al. Effect of aquatic exercise training on fatigue and health-related quality of life in patients with multiple sclerosis. Arch Phys Med Rehabil. 2012 Oct;93(10):1701-8.

Klefbeck B, Hamrah Nedjad J. Effect of inspiratory muscle training in patients with multiple sclerosis. Arch Phys Med Rehabil. 2003 Jul;84(7):994-9.

Knoop H, van Kessel K, Moss-Morris R. Which cognitions and behaviours mediate the positive effect of cognitive behavioural therapy on fatigue in patients with multiple sclerosis? Psychol Med. 2012 Jan;42(1):205-13.

Kos D, Duportail M, D’hooghe M et al. Multidisciplinary fatigue management programme in multiple sclerosis: a randomized clinical trial. Mult Scler. 2007 Sep;13(8):996-1003.

Krupp L. Fatigue is intrinsic to multiple sclerosis (MS) and is the most commonly reported symptom of the disease. Mult Scler 2006;12:367–8.

Learmonth YC, Motl RW, Sandroff BM, et al. Validation of patient determined disease steps (PDDS) scale scores in persons with multiple sclerosis. BMC Neurol 2013;13:37.

Mathiowetz VG, Finlayson ML, Matuska KM et al. Randomized controlled trial of an energy conservation course for persons with multiple sclerosis. Mult Scler. 2005 Oct;11(5):592-601.

Mohr DC, Goodkin DE, Bacchetti P et al. Psychological stress and the subsequent appearance of new brain MRI lesions in MS. Neurology.2000;55:55—61.31.

Mohr DC, Hart SL, Goldberg A. Effects of treatment for depression on fatigue in multiple sclerosis. Psychosom Med. 2003 Jul-Aug;65(4):542-7.

Mohr DC, Lovera J, Brown T et al. A randomized trial of stress management for the prevention of new brain lesions in MS. Neurology 2012;79(5):412-9.

Moss-Morris R, McCrone P, Yardley L, et al. A pilot randomised controlled trial of an Internet-based cognitive behavioural therapy self-management programme (MS Invigor8) for multiple sclerosis fatigue. Behav Res Ther 2012;50:415–21.

Mostert S, Kesselring J. Effects of a short-term exercise training program on aerobic fitness, fatigue, health perception and activity level of subjects with multiple sclerosis. Mult Scler. 2002 Apr;8(2):161-8.

Oken BS, Kishiyama S, Zajdel D et al. Randomized controlled trial of yoga and exercise in multiple sclerosis. Neurology. 2004 Jun 8;62(11):2058-64.

Penner IK, Raselli C, Stöcklin M, et al. The fatigue scale for motor and cognitive functions (FSMC): validation of a new instrument to assess multiple sclerosis-related fatigue. Mult Scler 2009;15–1509–17.

Pilutti LA, Greenlee TA, Motl RW, et al. Effects of exercise training on fatigue in multiple sclerosis: a meta-analysis. Psychosom Med 2013;75:575–80.

Rietberg MB, Van Wegen EE, Kwakkel G. Measuring fatigue in patients with multiple sclerosis: reproducibility, responsiveness and concurrent validity of three Dutch selfreport questionnaires. Disabil Rehabil 2010;32:1870–6.

Sage N, Sowden M, Chorlton E et al. CBT for chronic illness and palliative care: A workbook and toolkit. John Wiley & Sons: Chichester. 2013.

Skinner V, Wrycraft N. CBT fundamentals: Theory and cases. McGraw-Hill Education (UK): Maldenhead. 2014.

Smith MM, Arnett PA Factors related to employment status changes in individuals with multiple sclerosis. Mult Scler 2005;11:602–9.

Thomas S, Thomas PW, Kersten P et al. A pragmatic parallel arm multi-centre randomised controlled trial to assess the effectiveness and cost-effectiveness of a group-based fatigue management programme (FACETS) for people with multiple sclerosis. J Neurol Neurosurg Psychiatry. 2013 Oct;84(10):1092-9.

Turnbull JC, Kersten P, Habib M, et al. Validation of the Frenchay Activities Index in a general population aged 16 years and older. Arch Phys Med Rehabil 2000;81:1034–8.

van den Berg M, Dawes H, Wade DT et al. Treadmill training for individuals with multiple sclerosis: a pilot randomised trial. J Neurol Neurosurg Psychiatry. 2006 Apr;77(4):531-3.

van Kessel K, Moss-Morris R, Willoughby E, et al. A randomized controlled trial of cognitive behavior therapy for multiple sclerosis fatigue. Psychosom Med 2008;70:205–13.

Velikonja O, Curić K, Ozura A et al. Influence of sports climbing and yoga on spasticity, cognitive function, mood and fatigue in patients with multiple sclerosis. Clin Neurol Neurosurg. 2010 Sep;112(7):597-601.

Weinges-Evers N, Brandt AU, Bock M, et al. Correlation of self-assessed fatigue and alertness in multiple sclerosis. Mult Scler 2010;16:1134–40.

White CA. Cognitive behaviour therapy for chronic medical problems: A guide to assessment and treatment in practice. John Wiley & Sons Ltd. : Chichester. 2001.

Wingerchuk DM, Benarroch EE, O’Brien PC, et al. A randomized controlled crossover trial of aspirin for fatigue in multiple sclerosis. Neurology 2005;64:1267–9.